2019-nCOV situation: 10 Feb 2020

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Pandemic Threats and Health Emergencies

2019-nCOV situation: 10 Feb 2020

Welcome to this special issue of the newsletter where we highlight latest research and policy news and literature on 2019-nCVO situation

Please send your feedback, articles and reports, or questions you would like to share to Dr. Chadia Wannous via email  cwannous@yahoo.com  

Wishing you useful reading!
Chadia

2019-nCOV Outbreak Situation

 
Situation updates:
 
WHO situation report no 20 on 9 Feb

  • No new countries reported cases of 2019-nCoV in the past 24 hours.
  • Update on Cruise Ship Diamond Princess:

On 9 February, Japanese National Health Authorities provided WHO with a detailed update on the situation of the Cruise Ship Diamond Princess, currently harboured in Yokohama, Japan. Following confirmation of a case of 2019-nCoV, all crew and passengers are being quarantined for a 14-day period on board the vessel, asked to stay in their cabins and to wear a mask when leaving their cabin. All crew and passengers are closely followed-up and are medically examined and tested for 2019-nCoV when displaying any signs or symptoms suggestive of 2019-nCoV disease. The quarantine period will come to an end on 19 February. Epidemiological and environmental investigations are ongoing.
As of 8 February, 64 individuals were found to have been infected with 2019-nCoV among passengers and crew members. All individuals testing positive were disembarked and admitted for medical care in infectious disease hospitals in the Yokohama area. Close contacts of the infected passengers are asked to remain in quarantine for 14 days from last contact with a confirmed case. Thus, the quarantine period will be extended beyond the 19 February as appropriate only for close contacts of newly confirmed cases.
 

  • WHO RISK ASSESSMENT

China         Very High
Regional Level       High
Global Level          High

https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200209-sitrep-20-ncov.pdf

Novel coronavirus (2019-nCoV) situation as of 10 February 2020, 10:00 (CET)
http://who.maps.arcgis.com/apps/opsdashboard/index.html#/c88e37cfc43b4ed3baf977d77e4a0667

China’s National Health Commission Feb 10: Daily briefing on novel coronavirus cases in China
On Feb 9, 31 provincial-level regions on the Chinese mainland as well as the Xinjiang Production and Construction Corps reported 3,062 new cases of confirmed infections (including 2,618 in Hubei province), 4,008 new cases of suspected infections (including 2,272 in Hubei province), 296 new serious cases (including 258 in Hubei province), and 97 deaths (91 in Hubei province, 2 in Anhui province, 1 in Heilongjiang province, 1 in Jiangxi province, 1 in Hainan province, and 1 in Gansu province). 632 patients were released from hospitals after being cured, including 356 in Hubei province. 29,307 people who had had close contact with infected patients were freed from medical observation.
http://en.nhc.gov.cn/2020-02/10/c_76383.htm

Latest developments in epidemic control on Feb 9 (2)
China has stepped up efforts to curb the spread of the novel coronavirus (2019-nCoV). Here are the latest developments:
— The National Health Commission said on Feb 9 it received reports of 2,656 new confirmed cases of novel coronavirus infection and 89 deaths on Feb 8 from 31 provincial-level regions and the Xinjiang Production and Construction Corps.
The overall confirmed cases on the Chinese mainland had reached 37,198 by the end of Feb 8 and 811 people had died of the disease.
— A total of 2,649 patients infected with the novel coronavirus had been discharged from hospital after recovery by the end of Feb 8, the commission announced on Feb 9.
— Central China's Hubei, the hardest-hit province, reported 2,147 new confirmed cases of novel coronavirus infection and 81 new deaths on Feb 8, local health authorities said on Feb 9. The figure is 694 less compared with the new confirmed cases reported in the previous day.
— The mortality rate of the virus in Hubei stood at 2.88 percent, with the city of Tianmen and Wuhan having the highest death rates at 5.08 percent and 4.06 percent, respectively.
— The newly-built Leishenshan Hospital in Wuhan, the second in the city replicating Beijing's SARS treatment model, received on Feb 8 the first batch of patients infected with the virus. The two makeshift hospitals — Leishenshan (Thunder God Mountain) and Huoshenshan (Fire God Mountain), together can accommodate 2,600 beds.
— China released an application guide to solicit research and development projects on rapid test kits for the novel coronavirus. The on-site quick testing equipment and reagents should be able to identify confirmed infection among suspected patients within 1.5 hours to help prevent and control the epidemic. Research institutes, universities and enterprises can submit applications to the Ministry of Science and Technology from Feb 8 to 13.
http://en.nhc.gov.cn/2020-02/09/c_76385.htm

Daily novel coronavirus pneumonia cases drop outside epicenter province
http://en.nhc.gov.cn/2020-02/08/c_76364.htm

UK says two of its new coronavirus cases are healthcare workers
http://news.trust.org/item/20200210160748-1qlj6

Coronavirus cases may be 'tip of the iceberg' outside China - WHO
http://news.trust.org/item/20200210131557-xwqy8
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Consequences of the Outbreak on Economy

Coronavirus prompts Sony, NTT to join Barcelona congress exodus
http://news.trust.org/item/20200210153545-54urz

IMF warns of coronavirus hit to Japan's economy via tourism, trade
http://news.trust.org/item/20200210152513-rjs5f

Coronavirus to hit Canadian economy, affect oil prices, tourism - finance minister
http://news.trust.org/item/20200210145007-kdk5i

Apple iPhone maker Foxconn approved to resume Shenzhen plant production -source
http://news.trust.org/item/20200210150239-v8hfd

Nissan to halt production at Japan factory due to coronavirus
http://news.trust.org/item/20200210125526-ws6ax

Hundreds of Chinese businesses seek billions to contend with coronavirus -sources
http://news.trust.org/item/20200210150008-68712

FACTBOX-China takes major steps to prop up coronavirus-hit economy
http://news.trust.org/item/20200210105815-javxm

China should consider cutting benchmark deposit rates -cbank adviser
http://news.trust.org/item/20200210111247-tqh9e
------------------------------
Control Measures

Advance team of WHO experts arrives in China to probe coronavirus
http://news.trust.org/item/20200210144906-zdvuf

Global Grain conference in Singapore postponed due to coronavirus
http://news.trust.org/item/20200210151410-654cd
===========
China:

China moves further to boost medical supplies production
http://en.nhc.gov.cn/2020-02/09/c_76387.htm
 
Wuhan mayor estimates 5 million left Wuhan before city was quarantined
An Associated Press analysis of domestic travel patterns using map location data from Chinese tech giant Baidu shows that in the two weeks before Wuhan’s lockdown, nearly 70% of trips out of the central Chinese city were within Hubei province.
https://apnews.com/c42eabe1b1e1ba9fcb2ce201cd3abb72
 
-------------------------------
 
Scientific publications and reports and news

WHO cautions that transmission of the new coronavirus outside of China could increase
“It’s slow now, but it may accelerate,” Tedros Adhanom Ghebreyesus said during a press conference in Geneva. “So while it’s still slow there is a window of opportunity that we should use to the maximum in order to have a better outcome, and further decrease the progress and stop it.”
https://www.statnews.com/2020/02/08/who-cautions-coronavirus-transmission-could-increase-beyond-china

Fluctuating funding and flagging interest hurt coronavirus research, leaving crucial knowledge gaps
The waxing and waning interest in coronaviruses has perpetuated gaps in the scientific understanding of the pathogens. Scientists don’t know how long people remain immune to a coronavirus after being infected. There are still looming questions about transmission. There aren’t any drugs approved specifically to treat coronaviruses. Work begun to test existing drugs to see if they were effective against SARS was abandoned when that threat faded; having that information now would have given doctors in China help they badly need.
https://www.statnews.com/2020/02/10/fluctuating-funding-and-flagging-interest-hurt-coronavirus-research/

Scientists are racing to model the next moves of a coronavirus that's still hard to predict
https://www.sciencemag.org/news/2020/02/scientists-are-racing-model-next-moves-coronavirus-thats-still-hard-predict

Analysis and projections of transmission dynamics of nCoV in Wuhan
https://cmmid.github.io/ncov/wuhan_early_dynamics/index.html

Effectiveness of airport screening at detecting travellers infected with 2019-nCoV
We find that airport screening for initial symptoms, via thermal scanners or similar, on either exit or entry is unlikely to detect a sufficient proportion of2019-nCoV infected travellers in order to avoid entry of infected travellers and therefore the potential for seeding of local transmission
https://www.medrxiv.org/content/10.1101/2020.01.31.20019265v1
 
On Cruise Ship Quarantined In Japan, New Cases Could Reset The Isolation Clock
https://www.npr.org/2020/02/07/803843303/on-cruise-ship-quarantined-in-japan-any-new-cases-would-reset-the-isolation-cloc

Bats Carry Many Viruses. So Why Don't They Get Sick?
Their bodies make molecules that other mammals don't have, which help repair cell damage. And their systems don't overreact to infections, which keeps them from falling ill from the many viruses they carry (and also prevents conditions like diabetes and cancer).
This shows that it's not always the virus itself but the body's response to the virus that can make us sick, explains Wang.
Olival at EcoHealth Alliance says let's be clear: it's not the bats' fault that people are getting diseases. "They've just sort of coevolved with these viruses and these bugs that basically don't cause them any harm."
The problem, he says, is when the viruses jump to new species. And it's human activity that makes that likely to happen.
In wildlife markets, like the one in Wuhan, Olival says animals that would rarely mix in nature come together. A bat in a cage could be stacked over a civet. And those animals are then mixed with humans — for example, butchers handling animals without gloves.
"The way that we're coming into contact with these animals, hunting, selling, and trading them is to a scale that really we haven't seen before," he says.
And bat researchers stress that bats aren't just a possible source of viruses. They play a hugely important role in Earth's ecosystem. They eat tons of insects and pollinate plants and disperse seeds for hundreds of plant species. And they've found a way to coexist with the viruses they carry — which means, says Wang, that even though bats may be the source of viruses that affect humans, they could also be the source of potential therapies if we study their immune systems.
https://www.npr.org/sections/goatsandsoda/2020/02/09/803543244/bats-carry-many-viruses-so-why-dont-they-get-sick

Clinical characteristics of 2019 novel coronavirus infection in China
https://www.medrxiv.org/content/10.1101/2020.02.06.20020974v1

FACTBOX-Here is what WHO experts are watching on the coronavirus' spread
http://news.trust.org/item/20200210125626-bdne1

The race to produce a vaccine for the latest coronavirus
Even if scientists are too late for this outbreak, their work will not be wasted
https://www.economist.com/international/2020/02/06/the-race-to-produce-a-vaccine-for-the-latest-coronavirus
------------------------
WHO Technical guidance
https://www.who.int/emergencies/diseases/novel-coronavirus-2019/technical-guidance
 

--------------------------
Lancet Coronavirus Resource Centre
This resource brings together new 2019 novel coronavirus (2019-nCoV) content from acrossThe Lancet journals as it is published. All content listed on this page is free to access.

https://www.thelancet.com/coronavirus
 
Elsevier’s free health and medical research on novel coronavirus (2019-nCoV)
https://www.elsevier.com/connect/coronavirus-information-center
-----------------------

Training course:
WHO Critical Care Severe Acute Respiratory Infection Training
This course is intended for clinicians who are working in intensive care units (ICUs) in low and middle-income countries and managing adult and pediatric patients with severe forms of acute respiratory infection (SARI), including severe pneumonia, acute respiratory distress syndrome (ARDS), sepsis and septic shock. It is a hands-on practical guide to be used by health care professionals involved in critical care management during outbreaks of influenza virus (seasonal) human infection due avian influenza virus (H5N1, H7N9), MERS-CoV, nCoV or other emerging respiratory viral epidemics.
https://openwho.org/courses/severe-acute-respiratory-infection
 
 
 

 

 

Knowledge Sharing

Thank you for reading. If you have thoughts, feedback, story ideas, or questions you would like to share or interested in partnering with us on a special event coverage, please send a note to Chadia Wannous via email cwannous@yahoo.com  

 

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